Respiratory depression is a serious side effect of many opioids and is responsible for the lethality of these compounds. Despite there being no formal studies in to the physiological action of U47700 as same as this drug in humans anecdotal reports point to a propensity of U47700 to produce much stronger respiratory depression than heroin or morphine. This makes U47700 a dangerous compound and users need to approach with extreme caution. At low doses it is reported that slows the breath moderately but will not produce a very noticeable impairment.
This can quickly lead to fatal brain damage. U47700 like other opioids does produce a number of undesirable after effects that are colloquially known as the “crash”. These include agitation, irritability, negative emotional states, cognitive fatigue, difficulty thinking, anxiety, depression and lack of motivation. Higher doses and overdoses overpower the user with abnormal breathing patterns reported, shortness of breath and loss of consciousness.
However, the come down can cause depression and lethargy. As the negative effects are not well known and do not seem serious, then this drug can be seen as a safe option. However, long term use memory problems or even anxiety and depression. It can keep you awake for many hours and this can lead to cold and sore throats being more frequent for regular users. A drug offence can have a serious impact on your life as it can limit jobs you can apply for in some countries and prevent you from being able to travel to certain countries.
Physical effects you will notice after having this legal drug are spontaneous tactile sensations, vibrating vision, dehydration, difficulty urinating, temperature regulation suppression, increased heart rate, tactile enhancement, increased blood pressure, increased perspiration, and stimulation effect which mean that user’s physical energy level is increased and it encourages him to perform different activities such as running, dancing and climbing. The dosage of the substance must be specified according to the medical prescription. Its light dosage includes 125 to 175 mg, common dosage is 200-250 mg and strong dosage includes 250-400mg. Its effect lasts from two to four hours.
There can be kidney, liver and heart problems associated with long term use and it has lead to death in a number of cases. It is possible to get a dependence on the drug as well as building up a tolerance to it which can lead to more and more needing to be taken to get the same buzz from it. If you have a heart problem, blood pressure problems, asthma or epilepsy then the drug can cause very dangerous reactions in the body.
It is also worth noting that many ecstasy tablets are mixed with other drugs or chemicals and these can have very different effects to the pure drug which could be very problematic. They are often cut with amphetamines, caffeine or other cheaper substances and this can make them slower to react. The drug is illegal in many countries and use or possession can lead to fines or jail sentences.